The Institute of Research, Education, and Services on Addiction (IRESA) was established in 1992 as Center for Addiction Studies (CEA).  The purpose of IRESA is to promote and develop research, education, and services for substance use and other behavioral health conditions in Puerto Rico and the Latino communities in the United States.  It has conducted an array of initiatives in prevention and substance use treatment and recovery support services, criminal justice, homelessness, HIV, and workforce development.  In addition to these roles, the evolution of the Institute provides and excellent example of the seamless integration of research, education, and services in the substance use and behavioral health field.